Blar i Bergen Open Research Archive på forfatter "Nielsen, Birgitte"

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    • Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers 

      Nielsen, Birgitte; Kleppe, Andreas; Hveem, Tarjei Sveinsgjerd; Pradhan, Manohar; Syvertsen, Rolf Anders; Nesheim, John Arne; Kristensen, Gunnar S Balle; Trovik, Jone; Kerr, David J.; Albregtsen, Fritz; Danielsen, Håvard Emil (Peer reviewed; Journal article, 2018-04-18)
      Background: Nuclear texture analysis measuring differences in chromatin structure has provided prognostic biomarkers in several cancers. There is a need for improved cell-by-cell chromatin analysis to detect nuclei with ...

    • Chromatin organisation and cancer prognosis: a pan-cancer study 

      Kleppe, Andreas; Albregtsen, Fritz; Vlatkovic, Ljiljana; Pradhan, Manohar; Nielsen, Birgitte; Hveem, Tarjei Sveinsgjerd; Askautrud, Hanne Arenberg; Kristensen, Gunnar S Balle; Nesbakken, Arild; Trovik, Jone; Wæhre, Haakon; Tomlinson, Ian; Shepherd, Neil A.; Novelli, Marco; Kerr, David J.; Danielsen, Håvard Emil (Peer reviewed; Journal article, 2018-03)
      Background: Chromatin organisation affects gene expression and regional mutation frequencies and contributes to carcinogenesis. Aberrant organisation of DNA has been correlated with cancer prognosis in analyses of the ...